Company	Targets, Platforms	Indications	Lead Phase
Vigil Neuroscience, Inc.	Anti-TREM2 mAb, small molecule TREM2 agonist	Neurology, ALSP, cALD, Alzheimer's	I
CinCor Pharma, Inc.	Aldosterone synthase inhibitor	Uncontrolled Hypertension and high plasma aldosterone	II
Amylyx Pharmaceuticals, Inc.	Sodium phenylbutyrate/taurursodiol	ALS, Alzheimer's, Wolfram syndrome	NDA/MAA

Company	Targets, Platforms	Indications
Vigil Neuroscience, Inc.	Anti-TREM2 mAb, small molecule TREM2 agonist	Neurology, ALSP, cALD, Alzheimer's
CinCor Pharma, Inc.	Aldosterone synthase inhibitor	Uncontrolled Hypertension and high plasma aldosterone
Amylyx Pharmaceuticals, Inc.	Sodium phenylbutyrate/taurursodiol	ALS, Alzheimer's, Wolfram syndrome

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